Varicose veins are a common vascular condition that can negatively affect physical comfort and quality of life, prompting the need for effective non-invasive treatment approaches such as sequential pneumatic compression (SPC).

SPC therapy has emerged as a potential adjunct treatment for individuals with symptomatic varicose veins. In a randomized controlled study by Yamany and Hamdy (2016), 28 women with varicose veins were allocated to either an exercise-only group or an exercise plus SPC group. Both groups performed lower limb exercises targeting the calf, thigh, and ankle; however, the experimental group additionally received SPC therapy for 30 minutes per day, five days per week, over a six-week period.

Outcome measures included venous blood flow velocity, refilling time, pain intensity, and quality of life. The findings demonstrated significant improvements in both groups following the intervention; however, the group receiving SPC therapy showed greater increases in venous blood flow velocity, as well as more substantial reductions in pain levels and improvements in quality of life. No significant differences were observed between groups in refilling time.

The physiological effects of SPC are thought to be related to its ability to mimic the action of the calf muscle pump, thereby enhancing venous return and reducing venous stasis. This mechanism may also contribute to decreased edema and improved vascular function. Overall, the study suggests that the addition of SPC therapy to a structured exercise program may provide enhanced clinical benefits for individuals with varicose veins.